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5, the characteristic absorption peak at 584 nm for both M-CuP and D-CuP exhibited no statistically significant variation across the tested pH range

Indeed, during APAP-induced toxicity there is an increased generation of mitochondrial superoxide anion production, stimulated by impaired mitochondrial respiration and formation of adducts between the reactive metabolite NAPQI and sulfhydryls moieties from mitochondrial proteins (Yan et al., 2010)

A 5-fold increase of hepatic lipid peroxidation, 9.5-fold increase of plasma 8-isoprostane level and increased expression of hepatic metallothionein were observed (136)

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The FDA approved a label change to add the following ophthalmologic findings to subsection 5.1 (Warnings and Precautions